A β-lactone compound — globilactone A — has been discovered through genome mining and heterologous expression of a biosynthetic gene cluster. Biosynthetic investigations unveiled the mechanism of the formation of the cyclopentane-β-lactone core.
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References
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This is a summary of: Xu, Z. F. et al. Discovery and biosynthetic pathway analysis of cyclopentane–β-lactone globilactone A. Nat. Synth. https://doi.org/10.1038/s44160-023-00414-3 (2023).
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Biosynthesis of a β-lactone natural product globilactone. Nat. Synth 3, 17–18 (2024). https://doi.org/10.1038/s44160-023-00415-2
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DOI: https://doi.org/10.1038/s44160-023-00415-2
