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Plastics depolymerization

Designer catalytic nanopores meet PET nanoparticles

The search for novel biocatalysts for plastic degradation has recently become a hot topic. Now, multiple catalytic triads of well-known serine esterases were introduced into non-catalytic protein nanopores to enable the hydrolysis of PET nanoparticles.

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Fig. 1: Nanoporous FraC catalyses the degradation of PET nanoparticles.

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Acknowledgements

The authors would like to thank W. Liu of the Tianjin Institute of Industrial Biotechnology (TIB) of the Chinese Academy of Sciences for his assistance in preparing the structural files for the figure.

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Correspondence to Ren Wei.

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Wei, R., Bornscheuer, U.T. Designer catalytic nanopores meet PET nanoparticles. Nat Catal 6, 1105–1106 (2023). https://doi.org/10.1038/s41929-023-01072-6

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