Single-molecule break-junctions can detect RNA strands without requiring amplification or conversion to DNA with a limit of detection in the attomolar regime.
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Bouilly, D. Detecting short RNA sequences of pathogens. Nature Nanotech 13, 1094–1096 (2018). https://doi.org/10.1038/s41565-018-0303-z
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DOI: https://doi.org/10.1038/s41565-018-0303-z
