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From phage genetics to chromosomes as mechanical objects

Nancy Kleckner is the Herchel Smith professor of molecular biology at Harvard University. She recalls the evolution of her research interests from pure genetics, through biochemistry and molecular biology of DNA, to the roles of mechanical forces for whole-chromosome spatial patterning and dynamics.

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References

  1. Kleckner, N. et al. Proc. Natl Acad. Sci. USA 101, 12592–12597 (2004).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Chu, L. et al. Proc. Natl Acad. Sci. USA 117, 26749–26755 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Grinthal, A. Proc. Natl Acad. Sci. USA 107, 2467–2472 (2010).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Correspondence to Nancy Kleckner.

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Kleckner, N. From phage genetics to chromosomes as mechanical objects. Nat Cell Biol 25, 1075–1076 (2023). https://doi.org/10.1038/s41556-023-01200-1

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