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Trace element magnesium: a key player in hypertension management

Magnesium deficit decreases nitric oxide production and oxidative stress, but calcium efflux in VSMC enhances proliferation, migration, and remodelling. These pathways contribute to cardiovascular disorders, hypertension, insulin resistance, sodium retention, fluid retention, and blood volume. Magnesium supplements could be beneficial.

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Acknowledgements

Department of Biotechnology, School of Life Sciences, Central University of Tamil Nadu, supported by the Department of Science and Technology (DST) under the Scheme “Fund for Improvement of S&T Infrastructure (FIST)”. The Ramalingaswami Re-entry Fellowship (D.O. NO. BT/HRD/35/02/2006) awarded (2021) supported to Dr. Rajesh Parsanathan, from the Department of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India.

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Correspondence to Rajesh Parsanathan.

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Parsanathan, R. Trace element magnesium: a key player in hypertension management. Hypertens Res 46, 2442–2444 (2023). https://doi.org/10.1038/s41440-023-01404-w

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