The slow-release dexamethasone in proliferative vitreoretinopathy (PVR) prospective, randomized controlled clinical trial showed that a slow-release Dexamethasone injection given at the time of vitrectomy surgery and repeated at the time of oil removal does not increase the anatomic success rate at 6 months in eyes with rhegmatogenous retinal detachment with grade C PVR. There was also no change in visual acuity, however there was a statistical reduction in cystoid macular oedema. CI confidence interval.
Reference to original study: Banerjee, P. et al., 2017. Slow-Release Dexamethasone in Proliferative Vitreoretinopathy. Ophthalmology, 124(6), pp.757–767.
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Mostafa, I., Al-Zubaidy, M., Ghareeb, A. et al. Infographic: Slow-release dexamethasone in proliferative vitreoretinopathy (PVR). Eye 36, 352–353 (2022). https://doi.org/10.1038/s41433-021-01532-y
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DOI: https://doi.org/10.1038/s41433-021-01532-y
