El-Sayed K M, Cosgarea R, Sculean A, Doerfer C. Can vitamins improve periodontal wound healing/regeneration? Periodontol 2000 2023; DOI: 10.1111/prd.12513.

Vitamins especially A, B, E, and CoQ10, as well as vitamin combinations, could exert positive attributes on periodontal outcomes.

The aim of this article was to elaborate on whether or not vitamins improve wound healing/regeneration, summarising the current evidence from in vitro, animal and clinical studies, thereby shedding light on the knowledge gap in this field and highlighting future research needs. Although the review demonstrated the current heterogeneity in the available evidence and knowledge gaps, the findings suggested that vitamins, especially A, B, E, and CoQ10 , as well as vitamin combinations, could exert positive attributes on the periodontal outcomes in adjunct to surgical or nonsurgical periodontal therapy.