Abstract
Background: Pediatric critical illness hyperglicemia is associated with poor outcome. Tight glycemic control is still in discussion.
Aim: To study the association between hyperglicemia and complications for postoperative pediatric cardiac patients.
Patients and Methods Concurrent cohort study. We included patients admitted to the intensive care unit after congenital heart defects surgery from december 2008 to december 2009. Patients with preoperative diagnosis of diabetes or infection were excluded. Blood glucose levels were measured in all children during 72 hours. Hyperglycemia was defined as blood glucose ≥ 126 mg/dl. We defined 2 groups according to first glucose measurement: normo and hyperglicemic group. We calculated relative risk of postoperative complications in relation to hyperglycemia adjusting for age and complex congenital heart disease.
Results: A total of 88 patients entered the study; 55% were in the hyperglycemic group. Glucose levels were normalized at 72 hours for all patients without insulin. The postoperative complications rate was 50%; there were no significant differences between groups. Relative risk of postoperative complications associated with PICU admission hyperglycemia was 1,32 (95% CI: 0, 85-2,05). Relative risk adjusted for age and complex congenital heart disease was 1,01 (95% CI: 0,65-1,58).
Conclusion: Hyperglycemia is transient in postoperative pediatric cardiac patients, and is not associated with higher complications.
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Escalante, M., Carrasco, J., Cerda, J. et al. 620 Hyperglycemia and Postoperative Complications in Pediatric Cardiac Patients. Pediatr Res 68 (Suppl 1), 317 (2010). https://doi.org/10.1203/00006450-201011001-00620
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DOI: https://doi.org/10.1203/00006450-201011001-00620