Abstract
Improvement in imaging techniques over the last 15 years, high resolution CT scan and more recently MR, permit detection of small lesions of the central nervous system. CT and/or MR were performed in 28 children with TPP (5M, 23 F) and the findings compared to the literature. Percentage of organic lesions are shown in the table.
Both CT and MR were perfomed in 18 patients and identified organic lesions (OTPP) in 4 patients (3M 1F 1 hamartoma, 2 germinomas and 1 post-traumatic sequelae). In 10 cases only MR was performed and 1 girl with and expanding hypothalamic lesion (hamartoma) was detected. We conclude that despite improved techniques the incidence of organic lesions in females with TPP has not changed. We suggest MR should be the imaging technique of choice in the diagnosis of TPP because it gives a better image without radiation exposure.
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Domenice, S., Latronico, A., Albano, M. et al. 17 ETIOLOGIC DIAGNOSIS OF TRUE PRECOCIOUS PUBERTY (TPP) BY COMPUTED TOMOGRAPHY (CT) AND MAGNETIC RESONANCE (MR). Pediatr Res 36, 681 (1994). https://doi.org/10.1203/00006450-199411000-00075
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DOI: https://doi.org/10.1203/00006450-199411000-00075