Abstract
Celiac disease is a chronic illness that produces malabsortion, which can induce important undernutrition and alterations in calcium metabolism. We were interested in bone mineralization (BM) in celiac patients, with adequate compliance of dietetic treatment, at least during the last year. In 14 female celiacs an evaluation was carried out of the characteristics at birth, at the time of the diagnosis and at the start of this study. BM was measured in the whole body, spine and hip (trocanter. Ward' triangle and femoral neck) with a double isotopic densitometer (Norland). Results were compared with those obtained in 66 normal school age females of the same age. It was found that celiacs had less birth weight and lenght, less weight/age adequation and less body weight than controls. % of adequation of BM of whole body was significantly less than controls either in total bone mass as well as in bone mineral density (79.7 ± 19.6 vs 100.2 ± 18.3 and 91.7 ± 9.0 vs 100.3 ± 1.1% respectively), inspine (85.4 ± 20.5 vs 100.0 ± 19.3 and 75.7 ± 12.1 vs 100.0 ± 16.4% respectively) only in total bone mas in thochanter (73.5 ± 27.7 vs 100.0 ± 34.9), without differences in Ward's triangle and femoral neck. These results show the impact of celiac disease upon BM and consequently the risk of developing osteoposis during adult life.
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Muzzo, S., Leiva, L., Larrain, F. et al. 15 BONE MINERALIZATION OF SCHOOL AGE FEMALES WITH CELIAC DISEASE. Pediatr Res 36, 680 (1994). https://doi.org/10.1203/00006450-199411000-00073
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DOI: https://doi.org/10.1203/00006450-199411000-00073