Abstract
It is well known that most of the adolescents with CDGP reach a final height (FH) similar or slightly less than their target height (TH). In the present study we have evaluated the effect on FH of long term treatment with testosterone in 12 patients with CDGP. All patients received monthly injections of testosterone enantate (33-50 mg/month) during 26 ± 7.2 months. The chronological age at the onset was 14.85 ± 0.5 years of age with a SDS of height of -3.1 ± 0.8. There were not significant differences between adult height prediction according to the method of Tanner (165.7 ± 7.3) and Bayley Pinneau (170.6 ± 7.6). Growth pattern and sexual development were followed up to FH (gv < 1cm/yr or bone age > 17 yrs.) Patients reached a FH of 167.1 ± 7.2 without significant differences with TH (170.1 ±5.7) nor with previous final height predictions. In summary, patients with CDGP treated with long term period of testosterone reached an FH according to the prediction by Tanner and slightly lower than the method of Bayley Pinneau which was similar to their TH.
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Bergadá, I., Bergadá, C. 14 FINAL HEIGHT (FH) AFTER LONG TERM TREATMENT WITH TESTOTERONE IN PATIENTS WITH CONSITUTIONAL DELAY OF GROWTH AND PUBERTY (CDGP). (CDGP). Pediatr Res 36, 680 (1994). https://doi.org/10.1203/00006450-199411000-00072
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DOI: https://doi.org/10.1203/00006450-199411000-00072