Abstract
Thirty cryptorchid boys with pre-scrotal testes were divided in two groups: Group 1 (3 bil/12 unil)received hCG (750U/m2/dose)+hMG (100U/m2/dose) 2 times weekly, during 6 weeks; Group II (5 bil/10 unil) received only hCG. Surgical correction was necessary in 28 cases, 22 of wich had a testicular biopsy and subsequent hystomorphological analysis. Results were obtained in basal condition and at 3rd. and 6th. weeks of treatment. Peak values are showed:
T=topic C=cryptorch. Sperm=spermatogonia/50 tubes At=tubular area. LH(mUI/ml) FSH(mUI/ml) Testosterone (ng/dl) inhibin (UI/L). There was no advantage in hMG association. The hormonal level fell between 3rd 6th weeks (down-regulation). There was no correlation between inhibin levels and testosterone, spermatogonia or tubular area. Tubular area and number of spermatogonias were decreased on the affected side in relation to the topic testes and in bilateral cases in relation to the normal patterns.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Longui, C., Arnhold, I., Mendonca, B. et al. 13 INHIBIN GENERATION IN CRYPTORCHID (CRI) BOYS UNDER 4 YEARS OF LIFE. Pediatr Res 36, 674 (1994). https://doi.org/10.1203/00006450-199411000-00037
Issue Date:
DOI: https://doi.org/10.1203/00006450-199411000-00037