Abstract
Infants with IUCE have a higher incidence of SIDS. We studied the changes in the breathing pattern in infants with IUCE with four channel (HR, RR, O2 sat, nasal air flow) 12 hr pneumograms within 24 hrs after birth and on the 10th day. 18 full term non-asphxiated healthy newborns whose urine, meconium, or maternal urine tested positive for cocaine were included in the study. A control group of health newborns were also studied (n = 8).
There were no differences in the incidence of obstr. apnea, mean a length, longest apnea and O2 desaturations between day 1 & 10 in both groups. There were no differences between the control & cocaine group in any of the above variables on day 1 and day 10. There is an increase in the heart rate in both groups of infants by the 10th postnatal day. However, infants in the cocaine group have significant increase in apnea >6 seconds, apnea density (AD) and periodic breathing (PB) by the 10th postnatal day. Whether these changes in the breathing pattern in the cocaine group is due to an abnormal control of breathing is not clear and needs further investigation.
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Sasidharan, P., Heimler, R., Billman, D. et al. 203 BREATHING PATTERN OF INFANTS WITH INTRAUTERINE COCAINE EXPOSURE. (IUCE). Pediatr Res 36, 36 (1994). https://doi.org/10.1203/00006450-199407000-00203
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DOI: https://doi.org/10.1203/00006450-199407000-00203