Abstract
We compared the prognostic value of static Crs measured in the first 24 hr using a single breath airway occlusion technique (Le Souefet al, Am Rev Resp Dis 1984:129:552-6) with mean FiO2 in the first 12 hr in 48 ventilated new horn infants of median (range) birthweight 1270 (480-3500) g. In a further 33 infants, Crs measured before surfactant administration in the first 24 hr was compared to junior doctor's visual estimates of respiratory compliance (i) using a visual analogue scale (analogue Crs) and (ii) based on their assesments of tidal volume (V1 Crs).
Static Crs provides an estimate of repiratory discase severity which may be less distorted by ventilator management than indices based on blood gases, such as FiO2. Visual estimates of Crs by junior doctors were unreliable. Routine measurement of Crs may therefore be a valuable adjunct to clinical management.
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Stenson, B., Glover, R., Wilkie, R. et al. STATIC RESPIRETARY SYSTEM COMPLIANCE (CRS): AN EARLY INDEX OF PROGNOSIS AND DISEASE SEVERITY IN IHE NEWBORN. Pediatr Res 35, 278 (1994). https://doi.org/10.1203/00006450-199402000-00143
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DOI: https://doi.org/10.1203/00006450-199402000-00143