Abstract
We studied 81 pre-pubertal overweight children concerning their lipid profile and cardiovascular risk. Obesity was defined by NCHS weight/height ratio (W/H) ≥ 120% and divided by Sex (M,F) and obesity degree:Moderate Obusity (MO):W/H ≤ 135% (n=22), Great Obesity(GO): W/H ≥ 140% (n=59). Data derived from the lipid research clinics and lipid levels above 95th and below 5th percentile were defined as abnormal. The clasoification for hyperlipoproteinemia types was the Fredrickson's et al (1967). No sexual difference was found. GO had higher levels of triglycerides (TG) and lower levels of total cholesterol (CT) and high density lipoproteine (HDL) than the MO group. (TG × = 131.7, 111.9mg/dl; CTx=:159.4, 169.4; HDL x=30.9, 36.8mg/dl respectively for GO and MO). GO presented 51.8 % (n = 30) of TG, above the 95th percentile and MO 40.9%. Hypercholesteremia (CT ≥ 180rog/dl): GO 13.5% (8) MO 33.3%;HDL ≤ 5 percentile:GO 83,6% (n = 46) MO 63,6% (n = 14);LDL the majority of the two groups had normal levels. Dislipoproteinemias:GO type IV = 36% (n=18) IIa = 18% (n=9) IIb 12% (n=6) 24% of them had only HDL ≤ 5th percentile and 32% had cardiovascular familial antecedents. At GO only 10%(n=5) of children presented normal lipid levels. The MO group had lower level of dislipoproteinemias (type IV=13.6%) (n=3);IIb=13.6%(n=3); IIb=9% (n=2) and only 4.5% of them had cardiovascular familial antecedents.This group had 27 more children with normal lipids than GO. LDL/HDL and cholesterolAIDL ratios were higher at GO (MO 2.8 and 4.6 GO 3.4 and 5.2). The results indicate that great obesity presents higher indicense of dislipoproteinemias and higher personal and familial cardio vascular risk.
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Nolasco, M., Fisberg, M. CARDIOVASCULAR RISK AND LIPID PROFILE IN CHILDHOOD OBESITY.. Pediatr Res 33, 659 (1993). https://doi.org/10.1203/00006450-199306000-00028
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DOI: https://doi.org/10.1203/00006450-199306000-00028