Abstract
Sligth hypoxic-ischemic perinatal event can originated scare problems in later netirodevelopment, The aim of this job is to show the effects of two levels of hypoxia in a maze test resolution.
Three groups of newborn Wistar rats were placed in an exposure chamber. They were keep in their mothers' cages till weaning (day 21). Days 25 and 26 they were submitted to maze trials. After fasting from day 28 until 30th, they were submitted again to a new maze trial. The variable validating the anirrals' behaviour was the number of squares crossed in the maze resolution (SC). Results and statistical analisys (ANOVA) are as follows:
V5 group obtained a best profile in the learning capacity than V10 group. Number of errors (SC) decreased dramatically in V5 as happend wiht SH group, while V10 remained the same level of the first trial. However we are not sure if these effects can be exclusively related to the absence of presumed handicap rats who died, or to any other genetic/environmental factor.
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Carratalá, F., Moya, M. & Ferrer, E. INFLUENCE OF DIFFERENT MODERATE LEVELS OF NEONATAL HYPOXIA IN RAT BEHAVIOR. EFFECTS IN MAZE TEST RESOLUTION. Pediatr Res 32, 612 (1992). https://doi.org/10.1203/00006450-199211000-00044
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DOI: https://doi.org/10.1203/00006450-199211000-00044