Abstract
Persistent hyperinsulism in the newborn (NB) entails a risk of recurrent hypoglyaania and secondary neurological damage. When performing pancreatectomy, a 95% extirpation is advised to prevent recurrence of hyperinsulinism. Two female 6 year old patients are presented, submitted to 95% pancreatectomy in the NB period for hyperinsulinisim verified by determinations of insulin and plasma glucose and diagnosis of nesidioblastosis with components of endocrine dysplasia (Case A) and endocrine dysplasia with nesidioblastosis component (Case B). The following evaluations were dene: Anthropometric (weight, size:Table NCHS-WHO), neurologic and endocrine function; glyoemia (GLYC), insulinemia (INS), relation insulinemia uU/hO/glyoemia (mm/L) (RaliG) VN=6, peptide C (pepC) in fasting (0′) and postprandial (90′), test of tolerance to oral gluxee 1.75/kg (OGT) and digestive absorption study:carotenemia, d-xylosemia, and fat absorption balance (Van de Kamer test). Case A, stature 116 cm, weight 21 Kg p 50 (NCHS). Case B, stature 118 cm, p 75, weight 24 Kg p 90 (NCHS). Cases A and B had normal neurologic test.
In summary, in 6-year follow up, 95% pancreatectomy did not affect grewth, endocrine function or the classical parameters of digestive absorption. In case B, a slight increase BEL I/G was observed wihout clinical expression.
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Asenjo, S., Gleisner, A., Wilhelm, V. et al. 1 ENDOCRINE AND ABSORPTIVE FUNCTION AFIER 95% PANCREATECTOMY. 6-YEAR FOLLOW UP. 2 CLINICAL CASES. Pediatr Res 32, 249 (1992). https://doi.org/10.1203/00006450-199208000-00024
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DOI: https://doi.org/10.1203/00006450-199208000-00024