Abstract
Cerebral blood flow velocity (CBFV) is decreased in polycythemic newborns and it normalizes after PPET. To study the influence of polycythemia on peripheral blood flow velocity (PBFV) we measured PBFV and CBFV in 17 polycythemic newborns. Nine normocythemic infants served as controls. Blood flow velocity was measured prior to and at 3 and 24 hrs after PPET in the study group and at 3 and 24 hrs after birth in the controls. Flow velocities were recorded with a 5MHz bidirectional continuous wave velocimeter. Hct decreased from 72.5±4.0% to 59.0±1.5% after PPET. Peripheral mean flow velocity (AUC°) in polycythemic newborns did not differ from controls. Cerebral mean flow velocity was decreased in polycythemic newborns and normalized after PPET.
NS = Not Significant * P<0.05 ° AUC = Area Under the Curve Values at 24 hrs did not differ from values at 3 hrs. These data show that blood flow velocity is regulated by different mechanisms in different vascular systems.
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Maertzdorf, W., Tangelder, G., Slaaf, D. et al. 156 EFFECTS OF PARTIAL PLASMA EXCHANGE TRANSFUSION (PPET) ON PERIPHERAL AND CEREBRAL BLOOD FLOW VELOCITY IN POLYCYTHEMIC NEWBORN INFANTS. Pediatr Res 28, 303 (1990). https://doi.org/10.1203/00006450-199009000-00180
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DOI: https://doi.org/10.1203/00006450-199009000-00180