Abstract
Glucose/oxygen-quotient (G/O2) represents the fraction of oxygen consumption (VO2) required for complete oxidation of glucose that disappears from the glucose pool. G/O2 was determined in newborn infants from glucose disappearance rate (Rd). measured with stable isotopes, and VO2. Appropriate (AGA) and small (SGA) for gestational age low birthweight newborn infants, and infants of diabetic mothers (IDM) were studied at an age of 8±4 (mean±SD) hours. Gestational age, birthweight, VO2, Rd and G/O2 of each group are listed in the table (mean±SD, *p<0.05).
Conclusion: In contrast to preterm AGA infants, in preterm and term SGA and IDM infants a considerable part of oxygen consumption cannot be explained by glucose oxidation. Consequently, these infants oxidize substrates other than glucose soon after birth.
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Van Asselt, W., Baarsma, R., Chapman, T. et al. GLUCOSE/OXYGEN-QUOTIENT ON THE FIRST DAY OF LIFE IN LOW BIRTHWEIGHT NEWBORN INFANTS AND INFANTS OF DIABETIC MOTHERS. Pediatr Res 26, 523 (1989). https://doi.org/10.1203/00006450-198911000-00146
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DOI: https://doi.org/10.1203/00006450-198911000-00146