Abstract
To evaluate hemodynamic effects of PDA, left ventricular output (LVO) and BFV in the renal, mesenteric, ophthalmic and median cerebral arteries were serially measured (duplex pulsed Doppler) in 11 preterm normoventilated infants (GA 26-31 wks) during PDA and after ligation. While LVO increased, mean (m) diastolic (d) BFV's decreased gradually, whereas m-systolio BFV's did not change significantly. LVO and BFV's normalized after ligation. The decrease of renal and mesenteric mdBFV was earlier and larger than of cerebral mdBFV, and preceded clinical signs of PDA Similar changes of organ blood flow have been observed in lambs (Clyman et al, J Ped 111:579, 1987). Conclusion: Evaluation of regional BFV's yields additional information on the hemodynamic significance of a PDA in preterm infants.
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Lindner, W., Schindler, M., Versmold, H. et al. RENAL, INTESTINAL, CEREBRAL AND OPHTHALMIC BLOOD FLOW VELOCITIES (BFV) DURING PATENT DUCTUS ARTERIOSUS (PDA). Pediatr Res 26, 521 (1989). https://doi.org/10.1203/00006450-198911000-00132
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DOI: https://doi.org/10.1203/00006450-198911000-00132