Abstract
PD denotes episodes of diarrhoea that begin acutely, but persist beyond 15 days. Although the pathophysiology of PD remains unclear, it has been suggested to be related to the composition of the food ingested. The main objective of this study was to compare the clinical outcome in children with PD fed M or Y. The sample size calculated on the basis of 30% reduction in clinical failure (weight loss > 5% and intestinal intolerance) was 30 children with M and 26 children with Y. The 2 groups were ientical at randomisation (age = 8.2 months : duration of diarrhea = 20 days; number of stools = 6.3/day; weight/height = 85%). Following observations were made. 1) Clinical failure 13 (43%) in group M and only 3 (11%) in group Y (p < 0.01). 2) Weight gain was 44 + 48 g (x + SE) vs 152 + 95 (p < 0.02) in M and Y respectively. 3) Duration of diarrhea was 73 + 9hr in M and 40 + 8 in Y (p < 0.05); 4) liquid stool output was 40 + 8 in M vs 22 + 4 in Y. 5) Fluid intake was 62 + 7 ml/kg/d in M vs 39 + 5 in Y. 6) The amount of food intake including milk product intake was the same in oth groups i.e. 150 ml/kg/d in group M and 142 ml/kg/d in group Y. These results demonstrate a clinical advantage of feeding yogurt rather than milk in children with persistent diarrhea.
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Boudraaa, G., Touhami, M., Pouchart, P. et al. COMPARISON OF MILK (M) AND YOGURT (Y) IN CHILDREN WITH PERSISTANT DIARRHEA (PD). Pediatr Res 26, 276 (1989). https://doi.org/10.1203/00006450-198909000-00077
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DOI: https://doi.org/10.1203/00006450-198909000-00077