Abstract
ABSTRACT: Energy partitioned to maintenance plus activity, tissue synthesis, and storage was measured in 41 children in early recovery [W/L (wt/Iength)<5th percentile] from severe protein-energy malnutrition and in late recovery (W/L = 25th percentile) to determine energy requirements during catch-up growth. Metabolizable energy intake was measured by bomb calorimetry and metabolic collections. Energy expended (x± SD) for maintenance and activity estimated by the doubly labeled water method was 97 ± 12 kcal/kg FFM (fat-free mass) in early recovery and 98 ± 12 kcal/kg FFM in late recovery (p>0.5). Energy stored was 5-6 kcal/g of wt gain. Tissue synthesis increased energy expenditure by 1 ± 0.7 kcal/g gain in both early and late recovery. From these data a mathematical model was developed to predict energy requirements for children during catch-up growth as a function of initial body composition and rate and composition of wt gain. The model for predicting metabolizable energy requirements is [(98 x FFM + A (11.1 B + 2.2 C)], kcal/ kg.d, where FFM is fat-free mass expressed as a percentage of body wt, A is wt gain (g/kgd), B and C are percentage of wt gain/100 as fat and FFM, respectively. The model was tested retrospectively in separate studies of malnourished children.
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Fjeld, C., Schoeller, D. & Brown, K. A New Model for Predicting Energy Requirements of Children during Catch-Up Growth Developed Using Doubly Labeled Water. Pediatr Res 25, 503–508 (1989). https://doi.org/10.1203/00006450-198905000-00016
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DOI: https://doi.org/10.1203/00006450-198905000-00016
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