Abstract
Since Marshall report of the association between CP and gastritis or peptic ulcer there is a growing awareness of the CP presence in diseases of the stomach and duodenum.
We examined 44 children (26 Males) 5 to 17 yrs. old who had CP in antral mucosal biopsies. They had undergone gastroscopy for recurrent abdominal pain with or without vomiting or gastrointestinal bleeding. CP was identified in antral biopsies by Giemsa staining and a rapid urease test (CLO test-Delta West). At Endoscopy 17 showed a nodular pseudopolypoid pattern of the antrum and 27 a mild hyperemia and friability of the prepyloric mucosa. These antral lesions were associated with gastric ulcer in 8 cases, duodenal ulcer in 13, esophagitis in 26, duodenitis in 11. Multiple forceps biopsies were taken at sites of endoscopic damage. Histological examination of mucosal specimens showed: antral gastritis in 42 cases associated with peptic esophagitis in 13, Barrett's metaplasia in 2 and duodenitis in 11. In the same period antral gastritis was diagnosed in 65 children, CP was identified in 67% of them. No correlation was found between presence of CP and severity or type of antral inflammation.
CONCLUSION: in children CP can be associated non only with antritis and ulcer, but also with esophagitis duodenitis or Barrett's esophagus.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Oderda, G., Forni, M., Dell'Olio, D. et al. 71 CAMPYLOBACTER PYLORI (CP) AND UPPER GI ENDOSCOPIC AND PATHOLOGICAL CHANGES IN CHILDREN. Pediatr Res 24, 417 (1988). https://doi.org/10.1203/00006450-198809000-00094
Issue Date:
DOI: https://doi.org/10.1203/00006450-198809000-00094