Abstract
Gout patients are known to have risk factors which predispose to vascular disease, including hyperlipidaemia, hypertension, obesity and Type A personalities in association with hyperuricaemia and a high alcohol intake.
In this study a scoring system was devised in which risk factors for vascular disease were scored using scales based on the relative importance of these factors in the pathogenesis of vascular disease.
For each of 36 patients with primary gout a risk score was determined and each patient was advised and treated according to his or her own risk factors.
Patients were seen every three months, at which times their risk scores were recalculated and further advice given to see whether vascular risk could be reduced.
Risk scores ranged from 2 - 15, with a mean value on entering the study of 8.4. 9 patients reduced their risk score by 3 or more at one or more stage in follow up while 4 increased their score by 3 or more. Using paired t tests to compare risk scores for the group after various lengths of follow up there were significant falls in risk score at months 3 and 9 (p < 0.05 and < 0.002).
These results should be seen in the context of a small study but suggest that intensive counselling may beneficially affect risk scores for vascular disease in gout patients.
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Darlington, L., Scott, J. 26 CAN RISK SCORES FOR VASCULAR DISEASE IN COOT PATENTS BE IMROVED?. Pediatr Res 24, 115 (1988). https://doi.org/10.1203/00006450-198807000-00050
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DOI: https://doi.org/10.1203/00006450-198807000-00050