Abstract
Total daily energy expenditures (TDEE) of four exclusively breast-fed infants at 4 months of age were measured by the doubly-labeled water method. An oral dose of 300 mg of 18O and 200 mg of 2H2O/kg body weight was administered to these infants. Two baseline urine samples and two daily postdose urine samples were collected for 10-12 days. The 18O/16O and 2H/1H ratios of these urine samples were measured by isotope-ratio mass spectrometry. Diet-induced thermogenesis (DIT) and basal metabolic rates (BMR) of the sleeping infants were measured postprandially, 0-2 and 2-3 hr, respectively, by indirect calorimetry. Milk intakes of the infants were measured by the test-weighing technique. TDEE of the four infants averaged 69.0 ± 8.4 kcal/kg/d. DIT and BMR by indirect calorimetry averaged 0.5 and 49.3 ± 3.4 kcal/kg/d, respectively. Energy remaining for activity (activity = TDEE-DIT-BMR) in these infants averaged 19.2 ± 6.7 kcal/kg/d. Gross energy intake (0.67 kcal/g x milk intake, g/kg/d) was 79.4 ± 5.6 kcal/kg/d. Our preliminary results indicated that TDEE of these 4-month-old breast-fed infants was 87% of their daily gross energy intake. TDEE was partitioned into DIT (1%), BMR (71%), and activity (28%). The mean ratio of TDEE/BMR in these infants was 1.4 ± 0.1.
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Wong, W., Butte, N., Garza, C. et al. ENERGY EXPENDITURES OF TERM INFANTS DETERMINED BY THE DOUBLY–LABELED WATER (2H218O) METHOD, INDIRECT CALORIMETRY, AND TEST–WEIGHING. Pediatr Res 21 (Suppl 4), 282 (1987). https://doi.org/10.1203/00006450-198704010-00687
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DOI: https://doi.org/10.1203/00006450-198704010-00687