Abstract
We measured anthropometries, intellectual and motor functioning in 18 children (8 months - 15 years) before and one year after liver transplant. Depending on age at testing, we obtained Bayley Mental (MDI) and Psychomotor (PDI) Development Indices, or Stanford Binet IQ and Motor Age (MA), or Wechsler Verbal (VIQ) Performance (PIQ), and Full Scale (FSTQ) IQs on each subject. Weight (W), height (H), and head circumference for age (H/A, HC/A), and W for H (W/H) were expressed as percent of median (NCHS standards). Relevant findings were (Means):
No significant differences were found in mean development scores before and after transplant. However, for subjects with scores <80 before transplant, there was a trend towards improvement after transplant. Older subjects consistently improved in visual attention and fine motor speed. We conclude that there were significant increments in weight and head growth but no increase in linear growth. Intellectual and motor development remain unchanged for the group as a whole, although the most delayed made meaningful improvement. Long-term follow-up studies are indicated to determine ultimate intellectual outcome.
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Stewart, S., Uauy, R., Belknap, W. et al. ONE-YEAR FOLLOW-UP OF MENTAL/MOTOR DEVELOPMENT AND GROWTH IN CHILDREN AFTER SUCCESSFUL LIVER TRANSPLANTATION. Pediatr Res 21 (Suppl 4), 278 (1987). https://doi.org/10.1203/00006450-198704010-00666
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DOI: https://doi.org/10.1203/00006450-198704010-00666