Abstract
Three-hundred and forty albino Wistar rats, female, distributed at random for the formation of groups were studied: control pregnant (CP), undernourished pregnant (UP), control non-pregnant (CNP), undernourished non-pregnant (UNP). The groups were subdivided according to the time established for the study, i.e., with the sacrifice of animals with 0, 3, 6, 9, 10, 12, 15, 18 and 21 days. The control groups received “adlibitum” diets with 21% of casein protein, while the undernourished had a 50% reduction of the daily ingestion of the (CP) and only received 1% protein concentration. The growth hormone presented significant variation during pregnancy, while the caloric-protein undernourishment associated to pregnancy altered in a more significant way the rate of plasmatic rGH. While the control pregnant group, at the end of pregnancy, demonstrated an approximate increase of 80% in the rGH concentration, the undernourished presented an increase of approximately 200%. For the undernourished non-pregnant group, there was no significant alteration in relation to control, from the moment that nutrition restriction was imposed until its end. The sanguineous glucose for the pregnant groups demonstrated negative correlation in the course of time studied, nevertheless, the (CG) group presented percentually lower decrease in the glicemia during pregnancy, i.e. nutrition failure imposed on the pregnant rats aggravated the hypoglicemic state during pregnancy.
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Lippelt, R., Lippelt, R. & Nöbreqa, F. GROWTH HORMONE AND GLUCOSE IN THE PROTEIN-CALORIC UNDERNOURISHMENT OF THE PREGNANT RATS. Pediatr Res 22, 368 (1987). https://doi.org/10.1203/00006450-198709000-00027
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DOI: https://doi.org/10.1203/00006450-198709000-00027