Abstract
We have previously shown that neurodevelopmental progress at 1 year of age could be predicted with reasonable accuracy from brain ultrasound scans in a 5-year cohort of infants born at less than 33 weeks of gestation(1). We now report prediction of outcome at 4 years of age in the 172 infants born in the first 3 years of this study, 1979-'81. The results showed that the probability of a major disorder was 8% (95% confidence interval 4-14%) in 130 infants whose scans at discharge from the neonatal unit were ‘favourable’, i.e. gave no evidence of ventricular dilatation, hydrocephalus or cerebral atrophy (loss of brain tissue from any cause). By contrast, the probabilities of a major disorder were 38%(15-65%) in 16 infants with ventricular dilatation and 60%(30-84%) in 15 infants with hydrocephalus and/ or cerebral atrophy.
We conclude that predictions of outcome based on findings at 1 year have in.general been confirmed.
1. Stewart,A.L. et al. Dev Med Child Neurol., 1987; 29: 3-11.
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Costello, A., Hamilton, P., Baudin, J. et al. PREDICTION OF NEURODEVELOPMENTAL DISABILITY AT 4 YEARS FROM BRAIN ULTRASOUND APPEARANCE IN VERY PRETERM INFANTS. Pediatr Res 22, 220 (1987). https://doi.org/10.1203/00006450-198708000-00043
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DOI: https://doi.org/10.1203/00006450-198708000-00043