Abstract
Among the measures used to prevent bleeding from esophageal varices in children with PH, endoscopic sclerotherapy is becoming a most promising one. Nine children with a mean age of 6.7 years (range 3.4 - 9.2) with EPH were submitted to injection sclerotherapy. Before treatment, the mean number of bleeding episodes was 4.1 (range 1 - 11); and the mean lengh of time between bleedings was 5.6 months (range 0.5 - 16.8). All the children had grade III varices with red spots. A mean of 4.5 sessions (range 2 - 7) were performed at 3 to 4 weeks intervals. A volume of 0.5 to 2 ml of a 5% solution of ethanolamine oleate was injected in each varix. Following sclerotherapy, only transient mild complications were refered: fever in six children; hemoglobinuria in five; retrosternal pain in four; disphagia in one. Mean observation time after the begining of treatment was 15.4 months (range 9 - 26), during which no bleeding occurred. Endoscopies performed 6 months after last sclerotherapy session revealed grade I and few grade II esophageal varices. The differences between the means of the periods of time between bleedings before treatment and the post-treatment observation times were statistically significant (P < 0.01) (t test for paired samples). It is concluded that sclerotherapy is an effective measure in preventing variceal bleeding and improving the quality of life in children with EPH.
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Rodrigues, C., Salazar de Sousa, J. & Mendes, A. 65. ENDOSCOPIC SCLEROTHERAPY OF ESOPHAGEAL VARICES IN CHILDREN WITH EXTRAHEPATIC PORTAL HYPERTENTION (EPH). Pediatr Res 22, 107 (1987). https://doi.org/10.1203/00006450-198707000-00086
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DOI: https://doi.org/10.1203/00006450-198707000-00086