Abstract
Abdominal pain is a frequent symptom in school children. Since incomplete fructose absorption may be the cause, we studied fructose absorption by H2 breath tests in 205 unselected school children, i.e. 72 boys and 133 girls aged 10-19 years. The fructose load was 1 g/kg, max. 40 g, in a 10% solution. H2 values were corrected for atmospheric contamination and fasting levels. The results are shown in the table. Accompanying symptoms, which occured above 40 ppm peak H2 values, were mainly abdominal pain and flatulence.
In 10 families with a symptomatic index child we studied fructose absorption in parents and siblings. In each family we found at least one parent with symptomatic fructose malabsorption. Among the 21 children 12 showed incomplete and 9 complete fructose absorption. Conclusions: In school children incomplete fructose absorption is common and may be the cause of abdominal pain. Most likely the inheritance follows an autosomal dominant pattern.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Harms, H., Seidel, N., März, C. et al. 17. FREQUENCY AND INHERITANCE OF FRUCTOSE MALABSORPTION.A STUDY IN 205 UNRELATED SCHOOL CHILDREN AND 10 FAMILIES. Pediatr Res 22, 99 (1987). https://doi.org/10.1203/00006450-198707000-00038
Issue Date:
DOI: https://doi.org/10.1203/00006450-198707000-00038