Abstract
The aim of this study is to investigate the outcome of cow's milk intolerance and the possible development of multiple food intolerance. 43 children with C.M.I, were followed for periods varying from 7 to 72 months (mean 34 months). The age at onset of symptoms varied from 1 to 6 months. 14 presented immediate reactions to cow's milk and 29 delayed reactions. They were evaluated clinically and using skin prick test and RAST to milk and 15 other food allergens. The diagnosis of acquired C.M. tolerance or the development of multiple food intolerance was based on tests of elimination and challenge of milk and other proteins. To evaluate the outcome of C.M.I, we used the method employed for actuarial analysis of survival data. This revealed that the probability percentage of recovery from C.M.I. is 28% at 1 year from diagnosis, 79% at 2 years, 84% at 3 years and 95% at 4 years. After the third year from the diagnosis all Intolerant children presented multiple food intolerance.
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Scotta, M., Maggiore, G., Perversi, S. et al. A FOLLOW-UP STUDY OF CHILDREN WITH COW'S MILK INTOLERANCE. DEVELOPMENT OF MULTIPLE FOOD INTOLENCE. Pediatr Res 20, 701 (1986). https://doi.org/10.1203/00006450-198607000-00093
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DOI: https://doi.org/10.1203/00006450-198607000-00093