Abstract
A continuous 24 h esophageal pH monitoring, a non-agressive investigation technique in physiological circumstances, was performed in 200 asymptomatic infants between 5 days and 15 months old with a Memolog 600 system. During 24 h, 1 pH value every 7.5 s was stored in memory. Several parameters (refluxindex (RI), average duration of the longest reflux episode, number of all reflux episodes and those > 5 min) were studied in different groups of infants according to their age : 5–15 days old, 1, 2, 4, 6, 8, 15 months.
For all parameters we obtained significantly different results in infants younger and older than 4 months The RI e.g. in newborns is 1.16%. This index increases to 1.78% at 1 month, to 2.53% at 2 months. At 4 months differences are significant (P<0.01 to RI at 2 months; P<0.001 to RI at 1 month or neonatal) as the RI reaches 4.21%. At 6 months RI is 3.22%, at 8 months 3.85%. At 15 months finally RI decreases to 2.55% (P<0.01 to RI at 4 or 8 months). Our data stress the importance to establish age-related ranges for physiologic GER incidence in asymptomatic infants.
Similar content being viewed by others
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Vandenplas, Y., Sacré, L. CONTINUOUS 24 H ESOPHAGEAL pH MONITORING IN 200 ASYMPTOMATIC INFANTS (FROM 0 TO 15 MONTHS OLD). Pediatr Res 20, 692 (1986). https://doi.org/10.1203/00006450-198607000-00042
Issue Date:
DOI: https://doi.org/10.1203/00006450-198607000-00042