Abstract
A significant correlation between simultaneously determined SP and PP was found in 69 healthy adolescent girls (r=0.562, p < 0.001). 29 were still premenarchal (chronologic age -CA- 10.5-15, bone age -BA- 10-13.5 years -yrs-). 8 had anovulatory cycles (CA 12.8-21, BA 13-18, gynecologic age -GA- 0.1-6.7 yrs) and 4 presented primary and secondary amenorrhea (CA 12-18.8, BA 10-18 yrs). 17 with ovulatory cycles (CA 13-21.4, BA 13-18, GA 0.3-7 yrs) provided progesterone values during the follicular phase (FP) and 11 during the luteal phase (LP). SP and PP concentrations during FP did not differ from premenarchal girls or those with cyclic abnormalities. With respect to FP the coefficient of correlation between SP and PP was r=0.432 (n=58, p < 0.001). The correlation between SP and PP during LP was r=0.783 (n=11, p < 0.01). The regression equation of the log normally distributed values was y=3.49863+1.14611× (y=PP,x=SP). Provisional normal ranges for SP and PP during ovulatory cycles were established. During FP SP and PP ranged from 70-280 and 500-2400 pM/L, while the highest SP and PP levels during LP were 800 and 39000 pM/L. The Wilcoxon test was significant between progesterone during FP and LP both for SP (p < 0.05) and PP (p < 0.001).
Conclusion: Serial analyses of SP are suited to characterize phase and type of a cycle. Because of the high correlation it is possible to calculate PP during LP based on SP.
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Sorgo, W., Saur, G., Zachmann, M. et al. 198 SALIVARY (SP) AND PLASMA PROGESTERONE (PP) IN FEMALE ADOLESCENTS. Pediatr Res 19, 636 (1985). https://doi.org/10.1203/00006450-198506000-00218
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DOI: https://doi.org/10.1203/00006450-198506000-00218