Abstract
To determine the effect of timing and degree of diabetic control on neonatal morbidity, 115 insulin-dependent diabetic (IDDM) pregnancies were prospectively studied. Patients enrolled prior to 9 weeks gestation were randomly assigned to one of two groups with these management goals: I - strict control (FBS 60-80 mg%, 90 rain postprandial BS < 120) or II -customary control (FBS 80-100 mg%, 90 rain PPBS < 140). A group enrolled after the first trimester (HI) was managed identically to Group H. A nondiabetic group (IV) matched for race, gestational age, type of delivery and sex of neonate was analyzed for comparison. The following table lists percent incidence of neonatal complications:
We conclude that: 1) strict control reduces the incidence of hypoglycemia; 2) early control reduces birth asphyxia regardless of the type of control; 3) timing and type of diabetic control do not appear to affect the other neonatal complications listed.
* Clinical, chemical and radiographic criteria, a - IDDM vs. control, p < 0.05; b - strict vs. customary, p = 0.01; c - early vs. late, p < 0.001
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Ballard, J., Butler, J., Miodovnik, M. et al. 1329 EFFECT OF MATERNAL DIABETIC CONTROL ON NEONATAL MORBIDITY. Pediatr Res 19, 332 (1985). https://doi.org/10.1203/00006450-198504000-01353
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DOI: https://doi.org/10.1203/00006450-198504000-01353