Abstract
The concentrations of 22 elements (K, Ca, V, Cr, Mn, Pb, Ag, Zn, Fe, Cu, Rb, Ba, Al, Sr, Mg, Na, Sn, P, Ti, B, Ni, Co) were quantitatively determined in 88 pairs of maternal serum and amniotic fluid that were obtained simultaneously at 16-19 weeks gestation. The concentrations were determined by direct current plasma - atomic emission spectrophotometry (DCP-AES). A follow up of the 88 patients was made to obtain the birth weight, length and head size of their infants. Using concentrations of the element and the ratios of the element in maternal serum to that in the amniotic fluid as the independent variable, and physical parameters of the infants as the dependent variable, a set of multivariable equations was derived. The best equation (r=0.70) for predicting the birth weight was found to be: birth weight(gm) = 200 + 260, where ZS and AAF, represents concentration of Zn in maternal serum and amniotic fluid, respectively. Similarly, but to a lesser extent, the ratio of Fe in the maternal serum to Fe in the amniotic fluid accounted for 60% of the variance (r=0.60) in the birth weights. Several other equations will be presented as well.
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Hall, G., Lee, ML. 1292 PREDICTING BIRTH WEIGHTS FROM TRACE ELEMENTS IN MATEKNAL SERUM AND AMNIOTIC FLUID. Pediatr Res 19, 326 (1985). https://doi.org/10.1203/00006450-198504000-01316
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DOI: https://doi.org/10.1203/00006450-198504000-01316