Abstract
Selective Echo parameters have been used in separating children with VSD with and without pulmonary artery hypertension (PAH). This study was performed to assess specific Echo parameters in pts with endocardial cushion defects (ECD) with and without PAH. 22 pts (2 months - 11 years, 17 females/5 males) were compared with 27 normal controls (C). 5 pts had ASD I°, 3 pts had VSD of the ECD variety and 14 pts had complete A-V canal. Pts were divided into Group I (GI) 4 pts with pulmonary artery systolic pressure (PASP) <50 mm Hg; (GII) 18 pts with PASP ≥50 mm Hg. Differential tricuspid-mitral closure (ΔTc-Mc) was: (C) = 22 ± 8 msec, (GI) = 34 ± 12 msec, (GII) = -2 ± 15 msec (p < 0.001 as compared either with (C) or (GI)). ΔTc-Mc ≤10 msec was found in 0/4 pts of (GI), 15/18 pts of (GII). Right isovolumic contraction index (RICI = right ventricular pre-ejection period minus Q to tricuspid closure interval) was: (C) = −4 ± 9 msec, (GI) = -1 ± 9 msec, (GII) = 22 ± 18 msec (p <0.001 as compared with either (GI) or (C)). RICI ≥10 msec was found in 0/4 pts of (GI) and 13/18 pts of (GII). Utilizing both values of ΔTc-Mc ≤ 10 msec and RICI ≥10 msec, 17/18 pts with PAH of >50 mm Hg were recognized with no false positive. Thus, these two parameters (early tricuspid closure and increased right isovolumic contraction index) are useful in detecting PAH in children with ECD and could be used to optimize the time of cardiac catheterization.
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Young, ML., Ferrer, P., Pickoff, A. et al. DIAGNOSIS OF PULMONARY HYPERTENSION IN CHILDREN WITH ENDOCARDIAL CUSHION DEFECTS BY M-MODE ECHOCARDIOGRAPHY. Pediatr Res 18 (Suppl 4), 133 (1984). https://doi.org/10.1203/00006450-198404001-00240
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DOI: https://doi.org/10.1203/00006450-198404001-00240