Abstract
In this study we prospectively evaluated cardiac performance in 184 neonates admitted consequtively to neonatal intensive care because of early-onset respiratory disorder. We measured right and left ventricular systolic time intervals (RVSTI and LVSTI), blood pressure and heart rate at admission (2.9 + 0.8 h), at 5-7 h and at 24-26 h. Group A (N=161) consisted of term neonates with mild, moderate or severe transient tachypnoea (TTN), or with meconium aspiration (MA). Controls (N=14) were born through spontaneous vaginal delivery without medications. Group B (N=23) consisted of pre-term infants with severe IRDS. Controls (N=10) were pre-term infants without respiratory symptoms and increased FiO2-requirements.
In severe respiratory distress of term neonates, pulmonary hypertension is an early and important factor; later at the age of 6 h and thereafter, signs of impaired left ventricular performance emerge. In pre-term infants, restricted left ventricular performance appear at early stages of respiratory disease, and may be associated with insufficient maintenance of systemic blood pressure.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Heinonen, K., Hakulinen, A. EARLY SYSTOLIC TIME INTERVALS IN NEONATAL RESPIRATORY DISTRESS. Pediatr Res 18, 805 (1984). https://doi.org/10.1203/00006450-198408000-00079
Issue Date:
DOI: https://doi.org/10.1203/00006450-198408000-00079