Abstract
Patent ductus arteriosus(PDA)is an important negative factor in the clinical course of the VLBW infant with hyaline membrane disease(HMD). This study was designed to diagnose the PDA by CE1 and to close the PDA with oral indomethacin. In 78 VLBW infants with an umbilical artery catheter, the patency of the ductus arteriosus was determined by CE within the 1st 72 hrs of life. If the CE was positive for a PDA, indomethacin was adminstered in 2 doses of 0.15mg/kg OG 12 hrs apart. A 2nd CE was done following the 2nd dose to determine closure of the PDA. Results are:
The PDA can be determined simply by CE and oral indomethacin is effective in closing the PDA in most VLBW infants <72 hrs of age with HMD.
1. Zednikova, M., et al, Ped. Cardiol, Vol. 2, 1982
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Rhodes, P., Ferguson, M., Joransen, J. et al. DIAGNOSIS OF PATENT DUCTUS ARTERIOSUS IN VLBW INFANTS BY PRECORDIAL CONTRAST ECHOCARDIOGRAPHY(CE). Pediatr Res 18 (Suppl 4), 342 (1984). https://doi.org/10.1203/00006450-198404001-01494
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DOI: https://doi.org/10.1203/00006450-198404001-01494