Abstract
Summary: Cultured lymphocytes from children with kwashiorkor and from normal children were examined for their susceptibility to ultraviolet (UV)-induced chromosome aberrations, sister-chromatid exchanges and cell survival. Cells from kwashiorkor exhibited increased chromosome aberrations, but not sister-chromatid exchanges, when exposed to higher doses of UV. Furthermore, when cells from these patients were exposed to higher doses of UV, there was a significant reduction in viability. These results indicate that, as compared to normals, cells from kwashiorkor were more sensitive to the lethal effects of UV.
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Balakrishna Murthy, P., Abdul Rahiman, M. & Tulpule, P. UV-Induced Chromosome Aberrations, Sister-Chromatid Exchanges and Cell Survival in Cultured Lymphocytes from Malnourished Children. Pediatr Res 16, 663–664 (1982). https://doi.org/10.1203/00006450-198208000-00015
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DOI: https://doi.org/10.1203/00006450-198208000-00015