Abstract
Childhood SRNS has been reported to be associated with high incidence of atopy. Prevalence of allergic disease was studied in 51 children with SRNS. Thirty-eight healthy age and sex matched children and 60 children with urological disorders or urinary tract infection were controls. A standardized allergy questionnaire covering child and family was completed with parents of all patients and controls. Allergic symptoms included were asthma (A), urticaria (U), eczema (E), hay fever (H), contact dermatitis (C), drug or chemical allergy (D), and gastrointestinal (food) allergy (F). Positive family history was defined as finding symptoms in siblings, parents, aunts, uncles and grandparents.
Mean percentages of allergy prevalence were: SRNS patients: 15%, families: 32%; control children: 9%, families: 31%. No readily available explanation was found for the low prevalence of hay fever observed in this series. It is concluded that atopic symptoms seem to be more frequently present in SRNS children and their families than in controls. Pathogenic and therapeutic implications of allergic disease and SRNS require further study.
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Zilleruelo, G., Gallndez, R., Mitchell, M. et al. 1555 PREVALENCE OF ALLERGY IN STEROID RESPONSIVE NEPHROTIC STMDROME (SRNS). Pediatr Res 15 (Suppl 4), 702 (1981). https://doi.org/10.1203/00006450-198104001-01572
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DOI: https://doi.org/10.1203/00006450-198104001-01572