Abstract
The studies performed concerned the cause of severe infections and hypoimmunoglobulinemia observed in a 14 year old boy. The non-secretory plasmocytoma was detected. Data of immunological and other investigations are the subject matter of the paper. There were very low concentrations of serum IgA, IgM, IgG, IgE, not detectable IgD, and very low levels of chosen antibodies. Monoclonal protein and Bence-Jones protein were not found. Microscopic picture of bone marrow (using also immunofluorescent and electron-microscopy methods) was typical of the disease. The parameters of cellular immunity were normal.
The investigations indicate the rare cause of acquired hypogamma-globulinemia in children and stress the necessity of its early diagnosis.
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Golebiowska, H., Maj, S., Borysewicz, G. et al. Studies on hypoimmunoglobulinemia caused by unusual non-secretory plasmocytoma. Pediatr Res 13, 83 (1979). https://doi.org/10.1203/00006450-197901000-00082
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DOI: https://doi.org/10.1203/00006450-197901000-00082