Abstract
HbA1C was determined by a modification of a colorimetric method using thiobarbituric acid. The mean percent of HbA1C in a control non-diabetic population (n=26) was 6.44±0.2 (mean±SEM). The mean HbA1C percent of the diabetic patients group (n=40) was 9.31±0.38 (mean±SEM) and was significantly different from the normal group (P <0.001). There was no correlation between fasting blood (37 patients) and urinary (36 patients) sugar determination and HbA1C cone. obtained the same day (r=0.10 and r=-0.12, respectively). However, serial HbA1C determination over a 4-month period in 15 patients revealed a good correlation with the individual status of diabetic control, as evaluated by clinical and laboratory criteria. HbA1C colorimetric determination seems to be a simple, reproducible method which provides the clinician with an objective,useful indicator of carbohydrate control.
Article PDF
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sack, J., Chweidan, E., Theodor, R. et al. HbA1C determined by colorimetric method in the management of juvenile diabetic children. Pediatr Res 12, 1098 (1978). https://doi.org/10.1203/00006450-197811000-00100
Issue Date:
DOI: https://doi.org/10.1203/00006450-197811000-00100