Abstract
24 euthyroidal children suffering from idiopathic pituitary dwarfism were studied. The thyroidal situation was evaluated through the assay of T3,T4 and the use of the TRH test.All of the children were treated with HGH in 3 different ways. After no less than 16 months of treatment,and at intervals of 6 months, plasma T3 and T4 levels as well as TSH vasal conditions and after TRH were controlled. None of the children examined during the various checks presented the various indices at a pathological level simultaneously. These data seem to demonstrate that the risk of provoking an alteration in the thyroidal function through GH treatment is very slight.
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Cacciari, E., Cicognani, A., Pirazzoli, P. et al. Effect of long term GH administration on the pituitary-thyroidal function in idiopathic hypopituitarism. Pediatr Res 12, 1097 (1978). https://doi.org/10.1203/00006450-197811000-00093
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DOI: https://doi.org/10.1203/00006450-197811000-00093