Abstract
A significant rise of ICP during anesthesia has been reported in adults.(R.W.Adams et.al. 1972). This is believed to be due to the effects of halothane. We studied ICP changes in 9 infants undergoing surgery. The procedures were: herniorrhaphy in 6, ventriculo peritoneal shunt in 2 and anoplasty in 1. The age ranged from 7 days to 10 months and the weight ranged from 1.5 to 9 kg. ICP was measured via the anterior fontanel(AFP)using a previously described technique (Ped.59:957,1977). All received a mixture of halothane, N2O2 and O2 for anesthesia. The procedures lasted for 41.5±5.2 minutes. The mean±SE AFP before anesthesia (Pre.Anes) during awake intubation (Int.Awake) after a brief induction(Int.Indu.) during anesthesia(Du. Anes.) and post extubation (Post.Ext.) are shown in the Table.
The Δ rise in AFP during awake intubation was highly significant. (p<0.0001).AFP during the procedure remained higher as compared to pre.anes.levels(p<0.001). Post extubation AFP was normal. In 2 patients undergoing VP shunt there was a gradual fall in AFP during the procedure and in one of these ventricular fluid pressure and AFP were similar.(16.5 & 16.0Cm. H20). The data indicate: 1. A significant rise in AFP occurs during halothane anesthesia and 2. during awake intubation. 3. The rise in pressure persists during the procedure.
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Raju, T., Torres, C., Bennette, E. et al. 1149 INTRACRANIAL PRESSURE (ICP) MONITORING DURING GENERAL ANESTHESIA. Pediatr Res 12 (Suppl 4), 555 (1978). https://doi.org/10.1203/00006450-197804001-01155
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DOI: https://doi.org/10.1203/00006450-197804001-01155