Abstract
Eighty-three girls, ages 3 to 16 years, with recurrent urinary tract infections were randomly treated with Sulfamethoxazole-Trimethoprim (ST), Ampicillin (A), and Cephalexin (C) for 10 days. Criterions for inclusion were two consecutive urine cultures of greater than 100,000 colonies/ml and an organism sensitive to the test medication. Repeat urine cultures were obtained at three days, one week, two weeks (4 days post therapy), five weeks, nine weeks and 12 weeks.
Therapeutic success was defined as negative urine culture at the fourth day following completion of treatment. Recurrent bacteriuria was defined as two consecutive positive urine cultures at any time during follow up.
The measure of therapeutic success and recurrent bacteriuria was not affected by the presence of radiologic abnormalitied.
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Luengnarumitchai, M., Fennell, R., Richard, G. et al. 1087 A COMPARISON OF THE EFFICACY OF AMPICILLIN, CEPHALEXIN AND SULFAMETHOXAZOLE TRIMETHOPRIM IN THE TREATMENT OF GIRLS WITH RECURRENT BACTERIURIA. Pediatr Res 12 (Suppl 4), 545 (1978). https://doi.org/10.1203/00006450-197804001-01093
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DOI: https://doi.org/10.1203/00006450-197804001-01093