Abstract
The present study was done by analysing height channel recordings of diabetic children from two consecutive years, the midpoint being the time of the change in insulin therapy. The series includes all diabetics who presently attend the diabetes clinic and who had not passed midpuberty at the end of the analysis period. The patients were divided into two subgroups, a) lack of pubertal signs at the end of the analysis period (n=21) and b) early phase of puberty or midpuberty reached before the end of the analysis period (n=29). In group a) ten children had a decreased growth rate during the first year of analysis, and eight of them accelerated in height after the switch in insulin therapy The height increase/year was 4.7±0.4 before and 5.9±10.4 cm (mean ± SE) after the change. In group b) 12 diabetics presented growth deceleration during the year before the switch in therapy, and 11 of them accelerated after the change. Growth acceleration was related to improved control of diabetes. The findings indicate the value of twice daily insulin therapy in diabetic children.
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åkerblom, H., Koivukangas, T. GROWTH OF DIABETIC CHILDREN DURING TREATMENT WITH ONE AND TWO DAILY INJECTIONS OF INSULIN. Pediatr Res 9, 666 (1975). https://doi.org/10.1203/00006450-197508000-00011
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DOI: https://doi.org/10.1203/00006450-197508000-00011