Abstract
The role of hormonesin thermogenesis of the newborn is not known. Eight premature newborns (aged 12–72 hours and weighing 1080–2200 gr), who were admitted with rectal temperature ranging from 30.1–34.1°C (mean 32.8) were studied. Serum T4 iodine, GH.,I.,and blood glucose (BG) were determined during hypothermia (stage A) and when body temperature had been normal for at least 24 hours (stage B). The serum T4 values were significantly lower in stage A (1.8±55 mcg/100 ml), than in stage B (4.58±2 mcg/100 ml) with p <0.05. Serum I. values were also lower in stage A (13.57±6.7 μU/ml) than in stage B (21.4±4.9 μU/ml) with p <0.05, without analogous changes in BG concentration. GH concentration was not significantly different in stage A (23.7±9.4 ng/ml) than in stage B (16.5±5.1 ng/ml). The low levels of thyroxine may suggest a stage of decompesation or an inability to increase thyroid function appropriately upon exposure to cold.
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Dacou-Voutetakis, C., Anagnostakis, D., Chiotis, D. et al. HYPOTHEMIA OF THE NEWBORN:CHANGES IN THE LEVELS OF SERUM THYROXINE (T4) INSULIN (I) AND GROWTH HORMONE (GH). Pediatr Res 9, 688 (1975). https://doi.org/10.1203/00006450-197508000-00126
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DOI: https://doi.org/10.1203/00006450-197508000-00126