Abstract
The production rates (PR) (IU/24 hours), metabolic clearance (MCR) (mls/min.) disappearance (T 1/2) (hours) and excretion rates (% excretion) and Plasma testosterone (T) and Δ4 androstenedione concentrations (ng/100 ml) were measured in males with Precocious Puberty (PP), Delayed Puberty (DP), Hypopituitarism (HP), and Congenital Adrenal Hyperplasia (CAH).
We suggest that (1) in initiating puberty the LH PR rise precedes the plasma T rise and (2) precocious puberty might be a disorder of LH production.
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Maclaren, N., Akesode, F. & Raiti, S. PRODUCTION, METABOLISM OF FSH AND LH IN PUBERTY DISORDERS. Pediatr Res 9, 682 (1975). https://doi.org/10.1203/00006450-197508000-00092
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DOI: https://doi.org/10.1203/00006450-197508000-00092