Abstract
The regular pattern of early gross calcifications which are often present in the iliac arteries of the newborn children and infants depends on definite structural features of the arterial wall. The peculiar pattern of calcifications and the early appearance of the atherosclerotic lesions in the iliac arteries of children with a single umbilical artery also points to the significance of the structural features for the morphological aspect of early lesions. In the large muscular arteries, the gross and microscopic patterns of early calcifications are largely determined by the system of gaps in the internal elastic membrane which appear in an increasing number/with forthcoming growth. As could be shown at the common and internal carotid artery, the early lipid deposits are also initially confined to preformed structures of the arterial wall which develop not only at the arterial branchings but also in the straight arterial segments. The combined gross demonstration of the calcific and lipid deposits applied to several arterial segments may be helpful for the evaluation of the interrelation between the early calcifications and early lipids infiltrations.
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Mayer, W., Lind, J. EARLY FACTORS IN DEVELOPMENT OF ATHEROSCLEROSIS: EARLY LESIONS OF THE HUMAN ARTERIES IN RELATION TO THE ARTERIAL STRUCTURE. Pediatr Res 8, 130 (1974). https://doi.org/10.1203/00006450-197402000-00025
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DOI: https://doi.org/10.1203/00006450-197402000-00025