Abstract
Serum LH and FSH concentrations were determined in 16 normal girls (6-16 yrs of age) and 16 normal boys (9-18 yrs of age) and plotted against height and weight. There was a positive correlation between serum LH and height in girls (r=0.60; p < .01) and in boys (r=0.89; p < .005). A similar positive correlation was found between serum FSH and height in girls and boys (r=0.63; p < .005 for both sexes). A positive correlation was also observed between serum LH and weight in girls (r=0.60; p < .01) and boys (r=0.91; p < .005) and between serum FSH and weight in girls (r=0.47; p < .05) and boys (r=0.71; p < .005).More than two-thirds of the observed concentrations of LH and FSH fell within one standard deviation of calculated regression lines. Speculation: Cell mass can be predicted from the relationship between body composition and height and weight. From infancy to adolescence, there is a linear relationship between basal heat production and visceral cell mass. Serum LH and FSH concentrations would be expected to increase with height and weight if it is assumed that the attainment of a critical metabolic rate may be associated with reduced sensitivity of the hypothalamus to sex steroids giving rise to a change in the gonadal-hypothalamic feedback set-point.
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Penny, R., Olambiwonnu, N. & Frasier, S. CORRELATION OF SERUM LUTEINIZING HORMONE (LH) AND FOLLICLE STIMULATING HORMONE (FSH) CONCENTRATIONS WITH HEIGHT AND WEIGHT. Pediatr Res 8, 372 (1974). https://doi.org/10.1203/00006450-197404000-00194
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DOI: https://doi.org/10.1203/00006450-197404000-00194